In the early years of the conquest of the Americas, Inés Suárez, a seamstress condemned to a life of toil, flees Spain to seek adventure in the New World. As Inés makes her way to Chile, she begins a fiery romance with Pedro de Valdivia, war hero and field marshal to the famed Francisco Pizarro. Together the lovers will build the new city of Santiago, and they will wage war against the indigenous Chileans — a bloody struggle that will change Inés and Valdivia forever, inexorably pulling each of them toward separate destinies.